90% confidence interval for R_dnm [Study As­sess­ment]

posted by d_labes  – Berlin, Germany, 2019-01-07 16:17 (1958 d 20:05 ago) – Posting: # 19746
Views: 18,239

Dear Shuanghe,

❝ ❝ I would go with the formula of Rdnm

❝ ❝ R_dnm = r^(beta1 - 1)


❝ ...

❝ This must be it!

❝ According to his article, Smith use the formula EXP(beta0 + beta1*ln(dose)) to calculate each mean to get ratio Rdnm. so the value is Rdnm = 0.577402 (red digit from my sas). But this is equivalent to what you wrote so if you use the full precision figure we would have obtained the same values (90% CI of (0.477381, 0.698378)). I checked with the AUC data as well, they matches what's reported in table 2.


Could you please give a detailed example for what you did here?

Regards,

Detlew

Complete thread:

UA Flag
Activity
 Admin contact
23,029 posts in 4,834 threads, 1,644 registered users;
29 visitors (0 registered, 29 guests [including 6 identified bots]).
Forum time: 13:22 CEST (Europe/Vienna)

We must be careful not to confuse data with the abstractions
we use to analyze them.    William James

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5