Bioequivalence and Bioavailability Forum • TRT / RTR Design

TRT / RTR Design [RSABE / ABEL]

posted by Helmut – Vienna, Austria, 2017-05-03 00:04 (2982 d 03:59 ago) – Posting: # 17297
Views: 10,335

Hi Yura,

❝ […] reference-scaled average BE (RSABE) requires that the reference formulation be measured twice in each subject.

Says who?

❝ And therefore do not understand the legality of the calculation in this design.

Keep in mind that the early work on RSABE (by the two Lászlós) was solely based on exactly this design.

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Complete thread:

TRT / RTR Design Yura 2017-05-01 09:34 [RSABE / ABEL]
- TRT / RTR Design mittyri 2017-05-02 18:38
  - TRT / RTR Design Yura 2017-05-02 21:19
    - TRT / RTR DesignHelmut 2017-05-02 22:04
      - TRT / RTR Design Yura 2017-05-03 07:41
        
        TRT / RTR Design Helmut 2017-05-03 21:49
        
        TRT / RTR Design ElMaestro 2017-05-03 22:04
        
        TRT / RTR Design Helmut 2017-05-06 18:33
        
        TRR / RTT Design Yura 2017-05-09 11:35
        
        TRR / RTT Design Helmut 2017-05-09 13:06
        
        TRR / RTT Design Yura 2017-05-09 16:18
        
        TRR / RTT Design Helmut 2017-05-09 16:56
        
        TRR / RTT Design Yura 2017-05-09 17:36
        
        TRR / RTT Design Helmut 2017-05-09 17:53
        
        TRR / RTT Design Yura 2017-05-09 18:07

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