TRT / RTR Design [RSABE / ABEL]

posted by Yura – Belarus, 2017-05-01 09:34  – Posting: # 17285
Views: 6,719

Dear All
Do I understand correctly that using the TRT / RTR design it will be necessary to compare the RR and TT extension interval that are built on the data of subjects of different groups (50% of study subjects are used for RR and 50% of other subjects for TT), the comparison will be for different Subjects? Or will it be necessary to compare the extension interval R-R, built on 50% of the subjects, and the confidence interval T-R, built on the data of all subjects?
The appropriate sample size must be.
Alpha correction.
Best regards

Complete thread:

Activity
 Mix view
Bioequivalence and Bioavailability Forum |  Admin contact
19,514 posts in 4,141 threads, 1,336 registered users;
online 9 (0 registered, 9 guests [including 6 identified bots]).
Forum time (Europe/Vienna): 23:47 CEST

We must be careful not to confuse data with the abstractions
we use to analyze them.    William James

The BIOEQUIVALENCE / BIOAVAILABILITY FORUM is hosted by
BEBAC Ing. Helmut Schütz
HTML5