Bioequivalence and Bioavailability Forum

Calculate the BE limits for HVDPs based on EMA - libaiyi, 2018-06-08 11:41
- Calculate the BE limits for HVDPs based on EMA - Shuanghe, 2018-06-08 12:51
- (Expanded) BE limits, EMA-style - Helmut, 2018-06-08 13:19
  - (Expanded) BE limits, EMA-style - libaiyi, 2018-06-11 07:21
    - CFDA: Yet another story? - Helmut, 2018-06-11 12:24
      - CFDA: Yet another story? - libaiyi, 2018-06-12 11:09
        
        CFDA: Draft guidance? - Helmut, 2018-06-12 14:54
        
        CFDA: Draft guidance? - libaiyi, 2018-06-13 03:39
        
        Hypotheses generated “in face of the data” - Helmut, 2018-06-13 11:39
        
        Hypotheses generated “in face of the data” - libaiyi, 2018-06-14 03:46

[Opinion] Should the 90% CI for GMR be required to encompass 1 - bebac_fan, 2018-03-28 18:43
- [Opinion] Should the 90% CI for GMR be required to encompass 1 - ElMaestro, 2018-03-28 19:07
  - [Opinion] Should the 90% CI for GMR be required to encompass 1 - bebac_fan, 2018-03-28 19:23
    - [Opinion] Should the 90% CI for GMR be required to encompass 1 - ElMaestro, 2018-03-28 19:44
      - [Opinion] Should the 90% CI for GMR be required to encompass 1 - bebac_fan, 2018-03-28 20:05
        
        [Opinion] Should the 90% CI for GMR be required to encompass 1 - jag009, 2018-03-28 21:25
        
        [Opinion] Should the 90% CI for GMR be required to encompass 1 - bebac_fan, 2018-03-28 21:59
        
        [Opinion] Should the 90% CI for GMR be required to encompass 1 - ElMaestro, 2018-03-28 23:03
        
        [Opinion] Should the 90% CI for GMR be required to encompass 1 - bebac_fan, 2018-03-28 23:57
        
        Black Swan again - mittyri, 2018-04-05 17:57
- [Opinion] Should the 90% CI for GMR be required to encompass 1 - Helmut, 2018-03-28 23:57
  - [Opinion] Should the 90% CI for GMR be required to encompass 1 - bebac_fan, 2018-03-29 13:46
  - [Opinion] Should the 90% CI for GMR be required to encompass 1 - jag009, 2018-03-29 16:52
    - [Opinion] Should the 90% CI for GMR be required to encompass 1 - bebac_fan, 2018-03-29 16:57
      - [Opinion] Should the 90% CI for GMR be required to encompass 1 - jag009, 2018-03-29 19:55
        
        [Opinion] Should the 90% CI for GMR be required to encompass 1 - bebac_fan, 2018-03-29 20:30
        
        [Opinion] Should the 90% CI for GMR be required to encompass 1 - jag009, 2018-03-29 21:22
        
        Paper & Presentations - Helmut, 2018-03-30 01:33
        
        Donald Schuirmann’s opinion - Helmut, 2018-04-10 14:41

FDA: RSABE for NTID - Jay, 2018-03-26 13:31
- FDA: RSABE for NTID - jag009, 2018-03-26 17:57
  - FDA: RSABE for NTID - Jay, 2018-04-02 06:28
    - FDA: RSABE for NTID - pjs, 2018-04-02 15:07
      - FDA: RSABE for NTID - Jay, 2018-04-04 14:24
        
        β = 1 – π - Helmut, 2018-04-04 15:03

Full replicate designed study for Europe - balakotu, 2018-03-31 11:59
- Full replicate designed study for Europe - bebac_fan, 2018-04-01 04:45
  - Full replicate designed study for Europe - ElMaestro, 2018-04-02 02:19

95% Upper bound calculation - GM, 2018-03-07 06:25
- 95% Upper bound calculation - Katrin_Ti, 2018-03-09 14:05
  - 95% Upper bound calculation - GM, 2018-03-13 05:09
    - 95% Upper bound calculation - Katrin_Ti, 2018-03-13 09:31

question of adjustment - Yura, 2017-04-25 15:14
- TIE depends on CVwR (and n) - Helmut, 2017-04-26 14:17
  - TIE depends on CVwR (and n) - Yura, 2017-04-26 17:28
    - TIE depends on CVwR (and n) - Helmut, 2017-04-26 18:00
      - TIE depends on CVwR (and n) - Yura, 2017-04-26 18:55
        
        TIE depends on CVwR (and n) - Yura, 2017-04-28 11:13
        
        TIE = p(BE) at expanded limits - Helmut, 2017-04-28 19:16
        
        TIE = p(BE) at expanded limits - Yura, 2017-04-29 13:01
  - TIE depends on CVwR (and n) - pjs, 2018-02-28 14:33
    - TIE depends on CVwR (and n) - Helmut, 2018-02-28 14:48
      - TIE depends on CVwR (and n) - pjs, 2018-03-01 07:35
        
        Comparing methods for (S)ABE - Helmut, 2018-03-01 13:32
        
        Comparing methods for (S)ABE - pjs, 2018-03-05 14:50
        
        Simulating the Null - Helmut, 2018-03-05 17:40
    - Adjusting α - Helmut, 2018-03-07 16:21

Validation of FDA's RSABE on NTIDs - yicaoting, 2017-08-22 18:01
- Validation of FDA's RSABE on NTIDs - Helmut, 2017-08-22 20:25
  - Validation of FDA's RSABE on NTIDs - yicaoting, 2017-08-23 05:30
    - Validation of FDA's RSABE on NTIDs - Helmut, 2017-08-23 15:00
      - Validation of FDA's RSABE on NTIDs - yicaoting, 2017-08-30 14:33
        
        Validation of FDA's RSABE on NTIDs - Helmut, 2017-08-30 15:04
  - Clarification needed: Validation of FDA's RSABE on NTIDs - CECIF, 2018-02-19 22:20
    - FDA's RSABE on NTIDs in R - d_labes, 2018-02-20 14:10
      - FDA's RSABE on NTIDs in R - CECIF, 2018-03-01 21:08
        
        FDA's RSABE on NTIDs in R - Helmut, 2018-03-01 23:39

Which is better for missing periods PROC GLM or PROC MIXED - Mohamed Yehia, 2018-01-23 09:48
- EMA: Method A or B - Helmut, 2018-01-23 11:25
  - EMA: Method A or B - Mohamed Yehia, 2018-01-23 11:56

How to calculate N1,N2,N3 and DF in missing Partial replicate - Junior, 2018-01-22 20:33

Partial replicate or Reference scaling - heaven sent, 2017-12-29 17:24
- Partial replicate ≠ Reference scaling - Helmut, 2017-12-29 18:36

alpha correction - Yura, 2017-12-08 08:48
- theta0 within PE-constraints [theta1, theta2] - Helmut, 2017-12-08 12:33
  - theta0 within PE-constraints [theta1, theta2] - Yura, 2017-12-08 12:55

CI equation for 4 Period, 2 sequences "Full Replicate" - Mohamed Yehia, 2017-10-29 17:00
- DF for 4 Period, 2 sequences "Full Replicate" - Helmut, 2017-10-29 19:02
  - DF for 4 Period, 2 sequences "Full Replicate" - Mohamed Yehia, 2017-10-29 19:50

How To calculate CVintra and CVinter - Mohamed Yehia, 2017-08-15 15:33

only subjects with TR? - Helmut, 2017-07-11 21:34
- only subjects with TR? - zizou, 2017-07-12 23:12
  - only subjects with TR? - Helmut, 2017-07-13 20:32

WHO: scaling for AUC ? - Ohlbe, 2017-06-12 13:29
- WHO: Chapeau! - Helmut, 2017-06-12 23:31
  - WHO: Chapeau! - ElMaestro, 2017-06-13 00:08
    - WHO: Chapeau! - nobody, 2017-06-13 09:28

Calculation of Group effect for FDA studies - GM, 2017-06-09 08:10
- Calculation of Group effect for FDA studies - Beholder, 2017-06-09 09:58