Bioequivalence and Bioavailability Forum

Subject	Category	Author	posted	Replies	last R.	Views
⚠️ Read before registering 📌	Tips / Tricks	Helmut	2016-04-14 23:39	0		125,926
Spreadsheet failures, any recent examples? Spreadsheet failures, any recent examples? Spreadsheet addiction Nasty beast Nasty beast Nasty beast Nasty beast Decidedly off topic OT: R limbo 101 Spreadsheet addiction Spreadsheet addiction OT: Spreadsheet addiction OT: Spreadsheet addiction OT: Spreadsheet addiction OT: Spreadsheet addiction Spreadsheet etc. failures As designed ☺ As designed ☺ To round or not to round… To round or not to round… floating-point math is always more complex than you think it is Spreadsheet failures, any recent examples? Floating point arithmetic, again Floating point arithmetic, again Floating point arithmetic, again Floating point arithmetic, again Floating point arithmetic, again Floating point arithmetic, again Depressed Depressed Floating point arithmetic, again From bad to worse From bad to worse All is good Float is float Float is float! rational solution in R related stuff	Software	ElMaestro	2019-07-18 13:43	37	2021-01-14 12:53	6,817
Intra Subject Variability CVintra in replicate designs (→ 2 IBDs) Intra Subject Variability	General Statistics	clinicalservices	2021-01-05 08:19	2	2021-01-06 00:11	272
95% upper bound limit as per FDA for fully replicate crossover BE study 95% upper bound limit as per FDA for fully replicate crossover BE study 0.001 > 0 0.001 > 0	RSABE / ABEL	yogeshla	2021-01-05 07:01	3	2021-01-05 12:33	225
Definition of Generic Drug in Mexico	Regulatives / Guidelines	jag009	2021-01-05 00:25	0		135
Chinese BE GL Chinese BE GL Chinese BE GL no luck so far... Chinese BE GL HVD(P)s? HVD(P)s? China RSABE China DNS != Google DNS	Regulatives / Guidelines	Helmut	2020-12-30 11:37	8	2021-01-04 22:16	445
IVIVC in R Tutorials	Dissolution / BCS / IVIVC	Taonga Pomerai	2021-01-04 14:46	0		146
Simeticone soft gel capsule dissolution problem Simeticone soft gel capsule dissolution problem	Dissolution / BCS / IVIVC	mahonny	2015-03-31 13:12	1	2021-01-04 08:21	4,371
How to Increase Bioavailability on bebac?	Off Topic	rohit22	2020-12-25 17:05	0		202
Significant effects Significant effects: Don’t worry, be happy! Significant effects: Don’t worry, be happy!	General Statistics	Moloko	2020-12-22 11:41	2	2020-12-23 13:24	362
Inflated type I error with fixed widened limits? Inflated type I error with fixed widened limits? Inflated type I error with fixed widened limits? Inflated type I error with fixed widened limits Inflated type I error: Not nice Power of the GCC framework and power of PowerTOST Sample sizes (ignoring the inflated TIE) Bug? “Feature” Inflated type I error with fixed widened limits? Inflated type I error with fixed widened limits Inflated type I error with fixed widened limits Inflated type I error with fixed widened limits Houston, we have a problem! Paradox of tolerance Οὐτοπεία ∨ Εὐτοπεία Uchronia Steampunk Dieselpunk Dieselpunk Steampunk? OT Steampunk? OT PowerTOST 1.5.2.9000 on GitHub	RSABE / ABEL	Helmut	2020-11-25 10:50	22	2020-12-23 12:18	1,678
WHO frequent deficiencies in protocols and reports WHO frequent deficiencies in protocols and reports CI inclusion ≠ TOST CI inclusion ≠ TOST CI inclusion ≠ TOST CI inclusion ≠ TOST CI inclusion ≠ TOST CI inclusion operationally identical to TOST WHO lamenting about terminology? WHO lamenting about terminology? WHO lamenting about terminology? WHO frequent deficiencies in protocols and reports "obtain balanced groups" vs randomisation	Regulatives / Guidelines	Ohlbe	2020-12-04 12:04	12	2020-12-23 08:12	867
In memoriam László Endrényi 🥀 In memoriam László Endrényi 🥀	Off Topic	Helmut	2020-12-17 20:44	1	2020-12-18 11:15	362
Different sampling time points and Blinding Different sampling time points and Blinding Different sampling time points and Blinding Different sampling time points and Blinding Different sampling time points and Blinding Blinding…	Bioanalytics	Pharma_88	2020-12-11 05:22	5	2020-12-12 12:06	456
Pilot study “Bad” GMR “Bad” GMR	Power / Sample Size	konkous	2020-12-11 08:25	2	2020-12-11 14:44	439