FDA: PROC MIXED (‼) for ABE [Regulatives / Guidelines]

posted by Helmut Homepage – Vienna, Austria, 2021-09-17 19:11 (949 d 10:31 ago) – Posting: # 22584
Views: 2,741

Dear Mahmoud!

Dear Dr Helmut


Not a doctor. No intentions to become one. Told you that numerous times before.

❝ If SAS® is used for statistical analysis

❝ PROC MIXED should be used for fully replicated (4-way) BE studies

❝ PROC GLM should be used for partially replicated (3-way) BE studies


Since you didn’t bother to read the entire thread as suggested – and not even the subject line of my post – would you mind to digest this one?

Your quote refers to Reference-scaled Average Bioequivalence (\(\small{s_\textrm{wR}\geq 0.294}\)).
However, for (conventional, unscaled) Average Bioequivalence (\(\small{s_\textrm{wR}<0.294}\)) PROC MIXED should be used regardless the design.

Dif-tor heh smusma 🖖🏼 Довге життя Україна! [image]
Helmut Schütz
[image]

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

UA Flag
Activity
 Admin contact
22,993 posts in 4,828 threads, 1,657 registered users;
69 visitors (0 registered, 69 guests [including 7 identified bots]).
Forum time: 05:43 CEST (Europe/Vienna)

So far as I can remember,
there is not one word in the Gospels
in praise of intelligence.    Bertrand Russell

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5