yashokrajv
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2009-08-09 12:44
(5736 d 03:53 ago)

Posting: # 4022
Views: 10,709
 

 Intrasubject CV from Confidence interval and T/R [Power / Sample Size]

Dear all,

Is there a way to calculate the Intrasubject CV (ISCV) when we know the T/R ratio and confidence interval (power 0.8; level of significance 5%).
Since, many a times these information available in literature except for ISCV, would be useful to compare with our data.
Thanks in advance.

Ashok


Edit: Category changed. [Helmut]
Helmut
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2009-08-09 15:52
(5736 d 00:45 ago)

@ yashokrajv
Posting: # 4023
Views: 9,411
 

 CVintra from CI

Dear Ashok!

❝ Is there a way to calculate the Intrasubject CV (ISCV) when we know the

❝ T/R ratio and confidence interval (power 0.8; level of significance 5%).


Yes. You don't need the power in such a calculation - only the CI and the study's sample size (preferably the number of subjects / sequence also). T/R is optional. See these threads:David Dubins' FARTSSIE has an option to calculate CVintra from the point estimate and the CI for balanced (=equal number of subjects in each sequence) studies: Sheet [Bioequivalence, Crossover], Button ISV from Published Point Estimate and CI.

If you don't trust in M$-Excel, you can do a manual calculation as well - see one of my lectures (slides 12-15).

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yashokrajv
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2009-08-11 10:33
(5734 d 06:04 ago)

@ Helmut
Posting: # 4035
Views: 8,875
 

 CVintra from CI

Dear HS,

Thanks a lot. The Excel sheet is working wonderfully well!
Many thanks to Dr. Lenth and Dr. Dubins (who created this program).

regards
ashok
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