sample size calculation for higher level crossover design [Power / Sample Size]

posted by lovemysoul – Korea, 2012-11-07 06:34 (3981 d 09:18 ago) – Posting: # 9517
Views: 3,633

Dear all,

I have a question about sample size estimation for higher order x-over design.
When we calculate CV% of 2x2 design, MSE has to be calculated.

MSE = 2 x [(CI_high - PE) / {Root(1/nA + 1/ nB) x TINV(0.1,Df)}]^2

In case of 2x2 design, Df = nA + nB - 2

but Df of 6x3 williams design is 2n-4...

in case of 6x3 williams design, how can i get CV%? just change Df formula in MSE formula is enough?

and can i get a sample size of 2x2 crossover design using the data that i got from 6x3 williams design study?


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