Bioequivalence and Bioavailability Forum

Significance The Outlaw Torn 2012-11-20 07:56
- Significance ElMaestro 2012-11-20 08:17
  - Significance The Outlaw Torn 2012-11-20 08:55
    - Quality vs. Clinical ElMaestro 2012-11-20 09:04
- Sample size? Helmut 2012-11-20 20:10
  - Sample size? The Outlaw Torn 2012-11-21 07:52
  - Sample size? The Outlaw Torn 2012-11-22 10:55
    - Sample size, ratio, CV ↔ power Helmut 2012-11-22 13:35
      - Sample size, ratio, CV ↔ power The Outlaw Torn 2012-11-23 14:47
      - Sample size, ratio, CV ↔ power BEQool 2025-01-31 13:12
        
        TOST != treatment effect mittyri 2025-02-20 13:13
        Sample size, ratio, CV ↔ power zizou 2025-02-21 13:40
        
        Not vice versa mittyri 2025-02-22 21:08
        
        Not vice versa? zizou 2025-02-24 11:02
        
        Not vice versa? mittyri 2025-02-25 06:12
- Sample size calculation using Marzo and Balant method kumarnaidu 2013-01-31 07:48
  - Marzo / Balant formula d_labes 2013-01-31 10:05
    - Marzo / Balant formula kumarnaidu 2013-01-31 10:54
      - Marzo / Balant formula kumarnaidu 2013-02-04 05:48
        
        Marzo / Balant formula for parallel groups d_labes 2013-02-04 08:44

how to construct confidence interval for un-transformed metric? lizhao 2016-02-17 19:01
- how to construct confidence interval for un-transformed metric? jag009 2016-02-17 20:43
- how to construct confidence interval for un-transformed metric? mittyri 2016-02-17 22:34
  - Fieller’s confidence interval Helmut 2016-02-18 13:38
    - Fieller’s confidence interval lizhao 2016-02-22 20:20
      - Fieller’s confidence interval yjlee168 2016-02-23 08:23
      - Rescue approaching – PowerTOST d_labes 2016-02-23 09:08
        
        Rescue approaching – PowerTOST Weidson 2024-11-28 23:15
        
        Why not base 🇷? Helmut 2024-12-03 13:39
        
        Why not base 🇷? Weidson 2025-02-15 20:42

software for calculating sample size for replicate bioequivalence studies gsrao2022 2024-09-24 17:21
- 🇷 package PowerTOST Helmut 2024-09-24 19:33

Sequential Sample Size and Power Estimate in R xpresso 2023-09-19 13:40
- IUT Helmut 2023-09-19 14:04
  - IUT xpresso 2023-09-19 14:18
    - power is analytically accessible Helmut 2023-09-19 15:46
  - Power<50% BEQool 2024-03-01 14:26
    - Power<50% Helmut 2024-03-01 14:44
      - Power<50% BEQool 2024-03-01 23:02

Sample size calculation for NTI molecules narra1813 2019-08-10 09:21
- PowerTOST: sampleN.NTIDFDA() Helmut 2019-08-10 11:23
  - PowerTOST: sampleN.NTIDFDA() Mahmoud 2024-02-06 11:45
    - 'CVcap' Helmut 2024-02-06 13:51
      - sampleN.NTIDFDA(), power.NTIDFDA, pa.NTIDFDA are deprecated d_labes 2024-02-26 10:54

Power TOST question Achievwin 2024-02-20 19:49
- Power TOST question d_labes 2024-02-22 09:54
  - Power TOST question Achievwin 2024-02-22 18:34
    - Total sample size vs. vector of groups sizes Helmut 2024-02-23 10:06

sampleN.TOST vs. sampleN.scABEL BEQool 2024-01-29 11:53
- ABEL is a framework (decision scheme) Helmut 2024-01-29 13:52
  - ABEL is a framework (decision scheme) BEQool 2024-01-30 10:52
    - ABEL vs. ABE Helmut 2024-01-30 13:08
      - ABEL vs. ABE BEQool 2024-02-04 19:24
        
        Being able to read does not hurt… Helmut 2024-02-04 21:12
        
        Being able to read does not hurt… BEQool 2024-02-05 13:20
        
        Being able to read does not hurt… Helmut 2024-02-05 16:01
        
        Vet BE Guideline mittyri 2024-02-05 16:49

Go/No-go Decision for Pivotal Study NK 2023-12-27 12:15
- Problematic T/R-ratio… Helmut 2023-12-27 13:27
  - TSD? Helmut 2024-01-01 13:50
    - sample size for TSD is better than for 1SD? mittyri 2024-01-01 19:54

FDA: PD BE study balakotu 2023-07-12 04:24
- FDA: PD BE study dshah 2023-07-13 08:45

Sample size estimation for parallel design with more than 2 treatments BEQool 2023-05-24 21:05
- Sample size estimation for parallel design with more than 2 treatments dshah 2023-05-25 09:42
- >2 treatments, multiplicity or not Helmut 2023-05-27 08:26
  - >2 treatments, multiplicity or not BEQool 2023-05-29 10:41

Sample Size Benefits of Replicate Design with ABE Sereng 2023-05-24 15:41
- Sample Size Benefits of Replicate Design with ABE dshah 2023-05-25 09:56
- Dropouts less problematic Helmut 2023-05-25 16:27

R Validation Imph 2023-05-14 13:48
- R Validation Helmut 2023-05-15 11:54
  - R Validation Imph 2023-05-15 13:35
    - R Validation Helmut 2023-05-15 13:42

Sample size estimation for parallel design Nav Coelho 2007-07-20 16:14
- Parallel designs (total variance) Helmut 2007-07-20 16:29
  - Parallel designs (total variance) Nav Coelho 2007-07-20 18:38
    - CV-intra # 60% CV-inter Helmut 2007-07-22 01:17
    - total (pooled) variance: examples Helmut 2007-07-23 17:44
      - total (pooled) variance: examples Nav Coelho 2007-07-23 19:58
      - total (pooled) variance: examples BEQool 2023-04-18 09:59
        
        Higher-Order Crossovers Helmut 2023-04-20 10:19
        
        Higher-Order Crossovers BEQool 2023-04-21 07:53
        
        total (pooled) variance: examples zizou 2023-04-21 21:23
        
        total (pooled) variance: examples BEQool 2023-04-22 18:20
        
        total (pooled) variance: examples zizou 2023-04-22 21:06
        
        total (pooled) variance: examples BEQool 2023-04-25 10:57
        
        total (pooled) variance: examples zizou 2023-04-25 22:43
        
        total (pooled) variance: examples BEQool 2023-05-04 08:17
- Sample size estimation for parallel design Dipesh Jayswal 2007-07-24 08:52

Sample size for replicate crossover studies Imph 2023-03-06 14:29
- Sample size for replicate crossover studies dshah 2023-03-06 15:40
- Sample size for replicate crossover studies Helmut 2023-03-06 16:48
  - Sample size for replicate crossover studies Imph 2023-03-07 11:30

Deconvolution sample size and design issues mittyri 2023-02-09 14:40
- Deconvolution sample size and design issues dshah 2023-02-09 16:20
  - Deconvolution sample size and exponential terms mittyri 2023-02-09 22:08
    - Deconvolution sample size and exponential terms dshah 2023-02-10 09:34

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Pharmacokinetics may be simply defined as
what the body does to the drug,
as opposed to pharmacodynamics, which may be defined as
what the drug does to the body. Leslie Z. Benet

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