Bioequivalence and Bioavailability Forum

Sequential Sample Size and Power Estimate in R xpresso 2023-09-19 13:40
- IUT Helmut 2023-09-19 14:04
  - IUT xpresso 2023-09-19 14:18
    - power is analytically accessible Helmut 2023-09-19 15:46

FDA: PD BE study balakotu 2023-07-12 04:24
- FDA: PD BE study dshah 2023-07-13 08:45

Sample size estimation for parallel design with more than 2 treatments BEQool 2023-05-24 21:05
- Sample size estimation for parallel design with more than 2 treatments dshah 2023-05-25 09:42
- >2 treatments, multiplicity or not Helmut 2023-05-27 08:26
  - >2 treatments, multiplicity or not BEQool 2023-05-29 10:41

Sample Size Benefits of Replicate Design with ABE Sereng 2023-05-24 15:41
- Sample Size Benefits of Replicate Design with ABE dshah 2023-05-25 09:56
- Dropouts less problematic Helmut 2023-05-25 16:27

R Validation Imph 2023-05-14 13:48
- R Validation Helmut 2023-05-15 11:54
  - R Validation Imph 2023-05-15 13:35
    - R Validation Helmut 2023-05-15 13:42

Sample size estimation for parallel design Nav Coelho 2007-07-20 16:14
- Parallel designs (total variance) Helmut 2007-07-20 16:29
  - Parallel designs (total variance) Nav Coelho 2007-07-20 18:38
    - CV-intra # 60% CV-inter Helmut 2007-07-22 01:17
    - total (pooled) variance: examples Helmut 2007-07-23 17:44
      - total (pooled) variance: examples Nav Coelho 2007-07-23 19:58
      - total (pooled) variance: examples BEQool 2023-04-18 09:59
        
        Higher-Order Crossovers Helmut 2023-04-20 10:19
        
        Higher-Order Crossovers BEQool 2023-04-21 07:53
        
        total (pooled) variance: examples zizou 2023-04-21 21:23
        
        total (pooled) variance: examples BEQool 2023-04-22 18:20
        
        total (pooled) variance: examples zizou 2023-04-22 21:06
        
        total (pooled) variance: examples BEQool 2023-04-25 10:57
        
        total (pooled) variance: examples zizou 2023-04-25 22:43
        
        total (pooled) variance: examples BEQool 2023-05-04 08:17
- Sample size estimation for parallel design Dipesh Jayswal 2007-07-24 08:52

Sample size for replicate crossover studies Imph 2023-03-06 14:29
- Sample size for replicate crossover studies dshah 2023-03-06 15:40
- Sample size for replicate crossover studies Helmut 2023-03-06 16:48
  - Sample size for replicate crossover studies Imph 2023-03-07 11:30

Deconvolution sample size and design issues mittyri 2023-02-09 14:40
- Deconvolution sample size and design issues dshah 2023-02-09 16:20
  - Deconvolution sample size and exponential terms mittyri 2023-02-09 22:08
    - Deconvolution sample size and exponential terms dshah 2023-02-10 09:34

Bioequivalence Across 3 Different Injection Site XH7081 2022-09-21 20:22
- Bioequivalence Across 3 Different Injection Site dshah 2022-09-21 22:08
  - Bioequivalence Across 3 Different Injection Site XH7081 2022-09-22 17:14
- Two at a Time Helmut 2022-09-22 09:30
  - Two at a Time XH7081 2022-09-22 17:13
    - Two at a Time Helmut 2022-09-23 11:03

N calculation for trial about PK superiority alejandro_jo1990 2022-09-01 14:40
- Bracketing approach Helmut 2022-09-01 15:02
  - SmPC change is the whole thing alejandro_jo1990 2022-09-01 16:18
- N calculation for trial about PK superiority dshah 2022-09-02 11:52
  - The efocus is faster absorption alejandro_jo1990 2022-09-02 18:57
    - The efocus is faster absorption Helmut 2022-09-03 00:46
      - Non-parametric N alejandro_jo1990 2022-09-06 00:26
        
        Non-parametric N Helmut 2022-09-06 17:02
        
        Non-parametric N alejandro_jo1990 2022-09-15 14:56

Choosing formula for sample size Imph 2021-10-20 11:03
- Exact (Owen’s Q) Helmut 2021-10-20 11:36
  - Exact (Owen’s Q) Imph 2021-10-20 12:53
    - Exact (Owen’s Q) Helmut 2021-10-20 13:26
      - Exact (Owen’s Q) Imph 2021-10-24 10:41
        
        n iteratively from power Helmut 2021-10-24 10:54
        aproximate n d_labes 2021-10-24 19:26
      - Exact (Owen’s Q) Willem Talloen 2022-09-01 15:48
        
        PowerTOST & FDA Helmut 2022-09-01 16:31

Sample size for 3-way crossover chrisk 2022-08-09 18:55
- Sample size for 3-way crossover Helmut 2022-08-10 11:30
  - Sample size for 3-way crossover chrisk 2022-08-10 15:24
    - AND or OR, that’s the question Helmut 2022-08-10 15:58
      - AND or OR, that’s the question chrisk 2022-08-10 17:46
        
        AND or OR, that’s the question Helmut 2022-08-10 20:59
        
        AND or OR, that’s the question chrisk 2022-08-10 22:00
        
        AND or OR, that’s the question Helmut 2022-08-11 15:25
        
        AND or OR, that’s the question chrisk 2022-08-12 16:02
        
        The unknown ρ Helmut 2022-08-17 15:04

3 treatments with two-at-a-time approach chrisk 2022-08-01 07:03
- 3 treatments with two-at-a-time approach Helmut 2022-08-01 13:41
  - 3 treatments with two-at-a-time approach chrisk 2022-08-01 17:56

BCS Class II & IV molecule Mithu 2022-07-25 06:39
- BCS Class II & IV molecule dshah 2022-07-25 09:44
  - BCS Class II & IV molecule Mithu 2022-07-25 10:56
- in vivo ≠ in vitro Helmut 2022-07-25 09:56
  - in vivo ≠ in vitro Mithu 2022-07-25 10:54
    - in vivo ≠ in vitro dshah 2022-07-25 11:19
      - in vivo ≠ in vitro Mithu 2022-07-25 13:26
    - Assumptions Helmut 2022-07-25 13:02
      - Assumptions Mithu 2022-07-25 13:24

Sample size for the pilot study by the PASS2021 software dennis001 2022-07-24 10:56
- Pilot study (independent from software) Helmut 2022-07-24 12:27
  - Pilot study (independent from software) dennis001 2022-07-24 14:27
    - Rules of Thumb (PASS) Helmut 2022-07-24 14:55
      - Rules of Thumb (PASS) dennis001 2022-07-24 17:48

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