Bioequivalence and Bioavailability Forum • Potvin – all effects fixed (PHX/WNL resolved)

Potvin – all effects fixed (PHX/WNL resolved) [Two-Stage / GS Designs]

posted by Helmut – Vienna, Austria, 2012-11-06 14:48 (4612 d 03:05 ago) – Posting: # 9512
Views: 11,330

Hi ElMaestro!

❝ ❝ Sequence+Stage+Period(Stage)+Treatment+Sequence*Stage+Subject(Sequence*Stage)

❝ ❝ […] Don’t run the silly-o-meter on this setup.

❝

❝ Looks like this would kick the the silly-o-meter directly into a cosmic overdrive.

Definitely.

❝ I would intuitively say you should get the same results if you remove the Sequence (first) term. Can check?

Correct.

❝ By the way: If models need to be written anything like that then I would guess period would need to be specified as period(sequence) in the standard 2,2,2-BE model. Just trying to follow the logic that I don't understand. Nicht?

Nö (God moves in mysterious ways). Sequence+Treatment+Period+Subject(Sequence) works, whereas Sequence+Treatment+Period(Sequence)+Subject(Sequence) does not. In the magic BE-wizard LSMeans “not estimable” – end of story.

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Helmut Schütz

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Complete thread:

Potvin – all effects fixed (PHX/WNL vs. SAS, R) Helmut 2012-10-26 19:35 [Two-Stage / GS Designs]
- Potvin – all effects fixed (PHX/WNL vs. SAS, R) ElMaestro 2012-10-26 20:14
  - Potvin – all effects fixed (PHX/WNL vs. SAS, R) Helmut 2012-10-26 20:25
    - Potvin – all effects fixed (PHX/WNL vs. SAS, R) ElMaestro 2012-10-26 22:05
- Potvin – all effects fixed - SAS d_labes 2012-10-29 09:57
  - Potvin – all effects fixed (PHX/WNL resolved) Helmut 2012-11-06 01:43
    - Potvin – all effects fixed (PHX/WNL resolved) ElMaestro 2012-11-06 11:48
      - Potvin – all effects fixed (PHX/WNL resolved)Helmut 2012-11-06 13:48
        
        Mysterious ways ElMaestro 2012-11-06 15:27
        
        Mysterious ways Helmut 2012-11-06 17:06