Bioequivalence and Bioavailability Forum • Missunderstanding, crippled

Missunderstanding, crippled [RSABE / ABEL]

posted by ElMaestro – Denmark, 2012-10-11 20:12 (4635 d 12:44 ago) – Posting: # 9395
Views: 11,173
(edited on 2012-10-11 21:51)

Hi d_labes,

❝ I talked about evaluation using only the data for Reference (EMA crippled method)!

Did you just mean to prune away everything related to T1 and T2 and then run an analysis^*? It becomes more and more unclear to me what you actually wish to accomplish. I still haven't got the faintest clue why you wish to evaluate Ref against itself.

C = subset(A, tmt2!="T2" & tmt2!="T1") M2 = lm(C$logDATA~0 + as.factor(C$tmt2) + as.factor(C$subject) + as.factor(C$period) + as.factor(C$sequence)) coef(M2)

or did you mean sumfin entirely else?

If you use drop1(C, test="F") to get type III SS then you get basically the anova you pasted above. But we are only interested in the effect estimates not the source of variation, and the residual stays the same. So forget the type III SS approach - it is not necessary.

Edit: Massa! Why don’t you simply edit your post? [Helmut]

Hi Helmut: Yes, I screwed up a few times today when I somehow created a new entry rather than an edit :sleeping:

. It was borderline stupid, I admit. Please accept my apologies for causing overtime for you. Beer is on me next time we meet.

Yes, pleeeze! :party:

[Helmut]

—
Pass or fail!
ElMaestro

Complete thread:

Ref. vs. Ref. in partial replicate design d_labes 2012-04-25 15:52 [RSABE / ABEL]
- Ref. vs. Ref. in partial replicate design again d_labes 2012-10-10 10:56
- Ref. vs. Ref. in partial replicate design ElMaestro 2012-10-10 12:39
  - Ref. vs. Ref. in partial replicate design d_labes 2012-10-10 16:26
    - Ref. vs. Ref. in partial replicate design ElMaestro 2012-10-10 17:16
      - R vs. R in partial replicate design d_labes 2012-10-11 09:43
        
        R1 vs R2 ElMaestro 2012-10-11 10:26
        
        R1 vs R2 d_labes 2012-10-11 12:01
        
        R1 vs R2 ElMaestro 2012-10-11 12:09
        
        R1 vs R2 d_labes 2012-10-11 12:46
        
        treatment df ElMaestro 2012-10-11 13:38
        
        Missunderstanding d_labes 2012-10-11 16:34
        
        Missunderstanding, crippledElMaestro 2012-10-11 18:12
        
        EMA crippled method - R peculiarities d_labes 2012-10-12 14:54
        
        All is good, just forget ANOVA - you don't need it! ElMaestro 2012-10-12 16:25
        
        Just forget ANOVA. What next? d_labes 2012-10-15 08:35
        
        Just forget ANOVA. What next? ElMaestro 2012-10-15 10:04