Bioequivalence and Bioavailability Forum • Decision scheme without (?) power check

Decision scheme without (?) power check [Two-Stage / GS Designs]

posted by ElMaestro – Denmark, 2011-10-26 15:20 (4932 d 10:46 ago) – Posting: # 7546
Views: 18,394

Dear d_labes,

❝ What about this one (variant of Potvin B):

Alpha2 only kicks in when and if you know you are going into stage 2. Until then it is alpha1 everywhere. That would at least be least my understanding and intuition.

Best regards,
EM.

Complete thread:

2-stage design - power evaluation d_labes 2011-10-12 11:10 [Two-Stage / GS Designs]
- No opinions out there? d_labes 2011-10-26 09:14
  - Opinion yes, answer no ElMaestro 2011-10-26 11:15
    - Decision scheme without (?) power check d_labes 2011-10-26 13:00
      - Decision scheme without (?) power checkElMaestro 2011-10-26 13:20
        
        Decision scheme 'without' power check d_labes 2011-10-26 14:51
        
        Decision scheme 'without' power check ElMaestro 2011-10-26 15:24
        
        Numerical example d_labes 2011-10-26 16:28
        
        Numerical example ElMaestro 2011-10-26 16:49
        
        Potvin C with unsymmetrical alphas d_labes 2011-10-27 14:54
        
        Potvin B, C, or D? Helmut 2011-10-27 22:52
        Two-stage (classical Pocock) and the FDA Helmut 2011-10-31 02:36
- Weirdo paper ElMaestro 2011-11-30 18:04
  - Weirdo paper Helmut 2011-11-30 23:45
    - Weirdo paper ElMaestro 2011-12-01 07:16