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RegisterCV from previous study [Power / Sample Size]
Dear Rasheed
You should no use the CV. It is Intra Subject CV(ISCV)
Kindly use the ISCV for the parameter which is larger.
Then You shoud consider ISCV of Cmax for your Sample size calculations.
Regards
Bharat
Edit: Full quote removed. Please delete anything from the text of the original poster which is not necessary in understanding your answer; see also this post! [Helmut]
You should no use the CV. It is Intra Subject CV(ISCV)
Kindly use the ISCV for the parameter which is larger.
Ex: ISCV
Cmax 17%
AUC(0-t) 14%
AUC(0-inf) 11%Then You shoud consider ISCV of Cmax for your Sample size calculations.
Regards
Bharat
Edit: Full quote removed. Please delete anything from the text of the original poster which is not necessary in understanding your answer; see also this post! [Helmut]
Complete thread:
- CV from previous study rasheed 2010-04-08 08:53 [Power / Sample Size]
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- CV from previous studybharat 2010-04-08 13:57
- CV nick name d_labes 2010-04-08 14:23
- CV nick name(s) Helmut 2010-04-08 14:55
- CV nick name d_labes 2010-04-08 14:23
- Sample size based on largest CV for AR Helmut 2010-04-08 15:34
- any non BE resulting from AUCs? yjlee168 2010-04-08 21:44
- non BE resulting from AUCs: rarely Helmut 2010-04-08 23:48
- any non BE resulting from AUCs? yjlee168 2010-04-08 21:44
- CV from previous studybharat 2010-04-08 13:57
Ing. Helmut Schütz