Orouboros mixed up [RSABE / ABEL]

posted by Helmut Homepage – Vienna, Austria, 2010-03-09 15:55 (5539 d 21:31 ago) – Posting: # 4885
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Dear D Labes!

❝ Too bad I do not own WinNonlin.

❝ Can you eventually show some output of this method?


Well, we had a comparison following this post.

❝ What do you think about an adaption of


J.-P. Liu

Use of the repeated cross-over design in assessing bioequivalence

❝ Statist. Med. 14, 1067-1078 (1995)


Hhm, I don’t have it in my files yet.

❝ It has ANOVA tables but Liu term his model underlying the analysis "Mixed"!

❝ Mixed effects for subject and subject*formulation interaction.

❝ Without mixed effects the corresponding F-Tests would be others, I think.


Mixed is the taboo-word!


Edit: Got the paper. It’s definitely a mixed effects-model.

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