Bioequivalence and Bioavailability Forum • Sample size for a pilot study to estimate the CVintra

Sample size for a pilot study to estimate the CVintra [Power / Sample Size]

posted by yjlee168 – Kaohsiung, Taiwan, 2010-03-01 20:25 (5553 d 23:21 ago) – Posting: # 4843
Views: 13,511

Dear Helmut,

❝ ❝ how do we estimate the sample size?

❝

❝ Get the CV_intra from a pilot study.

a very interesting topic! Can this CV_intra from a pilot study really represent a CV_intra from a main study? What sample size will be required for a pilot study? Usually we use 4-6 subjects as the sample size in a BE pilot study here. I am confused by this question for a while. Thanks in advanced.

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-- Yung-jin Lee
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Complete thread:

Sample Size BA/BE Sriraj 2010-02-26 14:32 [Power / Sample Size]
- Sample Size BA/BE Helmut 2010-03-01 14:00
  - Sample size for a pilot study to estimate the CVintrayjlee168 2010-03-01 19:25
    - Sample size for a pilot study to estimate the CVintra Helmut 2010-03-01 21:01
      - Sample size for a pilot study to estimate the CVintra yjlee168 2010-03-01 23:47
        
        Sample size for a pilot study to estimate the CVintra Helmut 2010-03-03 19:04
        
        Sample size for a pilot study to estimate the CVintra yjlee168 2010-03-04 22:35
      - 80% confidence ? d_labes 2010-03-19 13:02
        
        75% confidence... Helmut 2010-03-19 14:12
    - Sample size for a pilot study to estimate the CVintra ElMaestro 2010-03-01 22:23
      - Sample size for a pilot study to estimate the CVintra yjlee168 2010-03-02 00:02
      - Sample size for a pilot study to estimate the CVintra Helmut 2010-03-02 02:19
        
        Sample size for a pilot study to estimate the CVintra yjlee168 2010-03-29 13:27
        
        Sample size for a pilot study to estimate the CVintra ElMaestro 2010-03-29 13:39
        
        Sample size for a pilot study to estimate the CVintra yjlee168 2010-03-29 13:47
        
        Sequential designs (history and future) Helmut 2010-03-29 14:19
        
        Sequential designs (history and future) yjlee168 2010-03-29 19:19
        
        Sequential designs (history and future) Helmut 2010-03-29 20:43
        
        Sequential designs (history and future) yjlee168 2010-04-01 18:58
        
        Sequential designs (WinNonlin vs. bear) Helmut 2010-04-02 21:00