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RegisterWhy not base 🇷? [Power / Sample Size]
Hi Helmut,
Congratulations! 🎉
Your script turned out excellent as well! Please accept my apologies for the delayed response.
In your opinion, based on this same example from the FDA guidance on VCA, how could I determine the statistical power for this analysis to assess the probability of rejecting the null hypothesis of bioinequivalence?
Would you happen to have a function ready at hand to provide this result? Based on these findings, what would be the required sample size for variation, according to Locke’s method, to ensure at least an 80% chance of rejecting the null hypothesis?
I was genuinely unable to find any article that explains how to determine the sample size and test power for the Locke method in the context of VCA studies.
"Looking forward to your insights!
Congratulations! 🎉
Your script turned out excellent as well! Please accept my apologies for the delayed response.
In your opinion, based on this same example from the FDA guidance on VCA, how could I determine the statistical power for this analysis to assess the probability of rejecting the null hypothesis of bioinequivalence?
Would you happen to have a function ready at hand to provide this result? Based on these findings, what would be the required sample size for variation, according to Locke’s method, to ensure at least an 80% chance of rejecting the null hypothesis?
I was genuinely unable to find any article that explains how to determine the sample size and test power for the Locke method in the context of VCA studies.
"Looking forward to your insights!
Complete thread:
- how to construct confidence interval for un-transformed metric? lizhao 2016-02-17 19:01 [Power / Sample Size]
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- how to construct confidence interval for un-transformed metric? jag009 2016-02-17 20:43
- how to construct confidence interval for un-transformed metric? mittyri 2016-02-17 22:34
- Fieller’s confidence interval Helmut 2016-02-18 13:38
- Fieller’s confidence interval lizhao 2016-02-22 20:20
- Fieller’s confidence interval yjlee168 2016-02-23 08:23
- Rescue approaching – PowerTOST d_labes 2016-02-23 09:08
- Rescue approaching – PowerTOST Weidson 2024-11-28 23:15
- Why not base 🇷? Helmut 2024-12-03 13:39
- Why not base 🇷?Weidson 2025-02-15 20:42
- Why not base 🇷? Helmut 2024-12-03 13:39
- Rescue approaching – PowerTOST Weidson 2024-11-28 23:15
- Fieller’s confidence interval lizhao 2016-02-22 20:20
- Fieller’s confidence interval Helmut 2016-02-18 13:38
Ing. Helmut Schütz