A rant [Two-Stage / GS Designs]

posted by Achievwin – US, 2024-08-28 04:16 (265 d 00:54 ago) – Posting: # 24166
Views: 1,684

I feel your pain, just curious if the two stage design went beyond 2x2 crossover or we are stuck in 1990s time? Any example how two stage adaptive design is applied/validated for parallel study or replicate design?

In case of parallel design what kind of statistical factor we need to use Potvin or Bonferroni and same for 4-period or 3-period replicate design?

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