Power TOST question [Power / Sample Size]

posted by d_labes  – Berlin, Germany, 2024-02-22 10:54 (115 d 18:07 ago) – Posting: # 23871
Views: 1,037

Dear Achievwin,

❝ When we use pa.ABE for parallel study N determination output gives N for certain power (e.g. if N=424 for 85% power) is this N is for total (N=424) or per arm (212+212)?

Call the man page of the function sampleN.TOST() and read under Details

The estimated sample size gives always the total number of subjects (not subject/sequence in crossovers or subjects/group in parallel designs – like in some other software packages)."

That is valid for all the other sample size estimating functions.

The power calculating functions accept a single number as sample size, here also the total.
Also accepted a vector of sample sizes, here meaning the sample sizes of groups.



Complete thread:

UA Flag
 Admin contact
23,057 posts in 4,840 threads, 1,641 registered users;
137 visitors (0 registered, 137 guests [including 78 identified bots]).
Forum time: 06:01 CEST (Europe/Vienna)

If you tell the truth you don’t have to remember anything.    Mark Twain

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz