sample size for TSD is better than for 1SD? [Power / Sample Size]

posted by mittyri – Russia, 2024-01-01 20:54 (54 d 19:33 ago) – Posting: # 23817
Views: 576

Hi Helmut,

naive question

Maurer(n1 = 24, CV1 = 0.0886, GMR1 = 0.84)

<...>

- Calculated n2 = 12

- Decision: Continue to stage 2 with 12 subjects


does it mean that TSD is more attractive due to lower sample size? That's significantly lower than 'Carved in stone'! I did not expect that with corrected PIE

Kind regards,
Mittyri

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