Asking a pupil [RSABE / ABEL]

posted by BEQool  – 2023-08-18 19:16 (190 d 21:15 ago) – Posting: # 23702
Views: 914

Dear Detlew,
thank you for the answer. I had read the whole article but I am still not getting it :confused:
Partial replicate design is a crossover design so we can get S2W (and consequently CVW) and because R is replicated we can also get S2WR (and consequently CVWR).
So why cant we get S2WT (and consequently CVWT) from the following equation:
S2W=(S2WT+S2WR)*2
as we only have one unknown (S2WT)?

"There is an infinite number of combinations of CVwT- and CVwR- values giving the same pooled CVw. We simply don’t – and can’t – know the variance components.
It’s like asking a pupil “We added two numbers and their sum was five. What were the two numbers?” Leaves the pupil – rightly – dazed and confused."

--> Refering to this, if we know that the sum (S2W) is 5 and one other number (S2WR; lets say it is 3), we can get the unknown number (S2WT; in this case we get 2)?

BEQool

Complete thread:

UA Flag
Activity
 Admin contact
22,911 posts in 4,806 threads, 1,635 registered users;
33 visitors (0 registered, 33 guests [including 3 identified bots]).
Forum time: 15:32 CET (Europe/Vienna)

The history of statistics is like a telephone directory:
the plot is boring, full of numbers and the cast is endless.    Stephen Senn

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5