Bioequivalence and Bioavailability Forum • T1E after 1st stage in Power2Stage

T1E after 1st stage in Power2Stage [Two-Stage / GS Designs]

posted by mittyri – Russia, 2022-06-24 21:05 (49 d 16:14 ago) – Posting: # 23083
Views: 770

Hi ElMaestro,

» Mixing up the terms alpha and T1E is a real danger for 2-stage approaches, since in "normal" trials they are one and the same.

yep, I should reformulate: T1E for the adaptive study finished after 1st stage due to BE goal reached (or some other reason to stop)

—
Kind regards,
Mittyri

Complete thread:

T1E after 1st stage in Power2Stage mittyri 2022-06-24 13:43 [Two-Stage / GS Designs]
- T1E after 1st stage in TSDs Helmut 2022-06-24 14:33
  - T1E after 1st stage in TSDs mittyri 2022-06-24 21:12
    - T1E after 1st stage in TSDs Helmut 2022-06-25 14:07
      - Potvin C consequences mittyri 2022-06-25 23:29
        
        Potvin C consequences ElMaestro 2022-06-26 09:11
        
        Potvin C consequences mittyri 2022-06-27 13:45
        
        Potvin C consequences Helmut 2022-06-27 14:49
        
        from Potvin C to Inverse Normal mittyri 2022-06-27 17:13
        
        From Potvin C to Inverse Normal: history (and outlook?) Helmut 2022-06-27 18:54
        
        Potvin C consequences ElMaestro 2022-06-27 17:13
        
        true CV ≠ observed CV mittyri 2022-06-27 17:22
- T1E after 1st stage in Power2Stage ElMaestro 2022-06-24 18:25
  - T1E after 1st stage in Power2Stagemittyri 2022-06-24 21:05
    - T1E after 1st stage in Power2Stage ElMaestro 2022-06-24 22:55