Dose-dependent CV? [Power / Sample Size]
❝ […] within subject coefficient of variation. Is it dose dependent?
If you have linear PK, generally yes. Otherwise, not necessarily.
❝ Can I take a coefficient of variation from a study done on a 500mg dosage and use it to calculate the number of subjects in a trial that will be done on a 1000mg dosage.
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
The quality of responses received is directly proportional to the quality of the question asked. 🚮