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RegisterDose-dependent CV? [Power / Sample Size]
posted by Helmut 
– Vienna, Austria, 2022-01-23 15:46 (1258 d 14:58 ago) – Posting: # 22744
Views: 3,141
Hi Imph,
If you have linear PK, generally yes. Otherwise, not necessarily.
See above.
❝ […] within subject coefficient of variation. Is it dose dependent?
If you have linear PK, generally yes. Otherwise, not necessarily.
❝ Can I take a coefficient of variation from a study done on a 500mg dosage and use it to calculate the number of subjects in a trial that will be done on a 1000mg dosage.
See above.
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Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- Intrasubject coefficient of variation Imph 2022-01-23 14:21 [Power / Sample Size]
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Dose-dependent CV?Helmut 2022-01-23 14:46
- Dose-dependent CV? Imph 2022-01-23 14:55
- Dose-dependent CV?Helmut 2022-01-23 14:46
Ing. Helmut Schütz