Intrasubject coefficient of variation [Power / Sample Size]

posted by Imph – Algeria, 2022-01-23 15:21 (379 d 14:56 ago) – Posting: # 22743
Views: 994

Please I have a question regarding the within subject coefficient of variation. Is it dose dependent? Can I take a coefficient of variation from a study done on a 500mg dosage and use it to calculate the number of subjects in a trial that will be done on a 1000mg dosage. Thank you in advance.

Complete thread:

UA Flag
 Admin contact
22,481 posts in 4,710 threads, 1,603 registered users;
25 visitors (0 registered, 25 guests [including 7 identified bots]).
Forum time: 06:17 CET (Europe/Vienna)

The difference between a surrogate and a true endpoint
is like the difference between a cheque and cash.
You can get the cheque earlier but then,
of course, it might bounce.    Stephen Senn

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz