aproximate n [Power / Sample Size]

posted by d_labes  – Berlin, Germany, 2021-10-24 19:26 (210 d 01:51 ago) – Posting: # 22656
Views: 978

Dear Imph,

beside to all what Helmut has told you you may find in the /doc directory of the package a PDF file "BE_power_sample_size_excerpt.pdf" which has some small further informations about the sample size estimation.

You may obtain an approximation of n by using the large sample approximation.
See P. Zhang
“A simple formula for sample size calculation in equivalence studies.”
J. Biopharm. Stat. 2003 Aug;13(3):529-38
This approximate number is in many cases relatively close to the exact value, and is used in PowerTOST as starting value of the iterative search of the sample size.

Regards,

Detlew

Complete thread:

UA Flag
Activity
 Admin contact
22,091 posts in 4,630 threads, 1,566 registered users;
online 45 (0 registered, 45 guests [including 36 identified bots]).
Forum time: Sunday 21:17 CEST (Europe/Vienna)

Competence, like truth, beauty and contact lenses,
is in the eye of the beholder.    Laurence J. Peter

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5