Probability to pass multiple studies [Power / Sample Size]

posted by Helmut Homepage – Vienna, Austria, 2021-02-19 12:02 (239 d 20:24 ago) – Posting: # 22214
Views: 1,341

Dear all (and esp. our expert in probability zizou),

say, we have n studies, each powered at 90%. What is the probability (i.e., power) that all of them pass BE?

Let’s keep it simple: T/R-ratios and CVs are identical in studies 1…n. Hence, p(1) = … =p(n). If the outcomes of studies are independent, is p(pass all) = Π p(i), e.g., for p(i=1…6) = 0.90 = 0.906 ~ 0.53?
Or does each study stand on its own and we don’t have to care? :confused:

Dif-tor heh smusma 🖖
Helmut Schütz
[image]

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

Activity
 Admin contact
21,730 posts in 4,544 threads, 1,543 registered users;
online 12 (0 registered, 12 guests [including 7 identified bots]).
Forum time: Sunday 09:26 CEST (Europe/Vienna)

Be very, very careful what you put into that head,
because you will never, ever get it out.    Thomas Wolsey

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5