Couple of sample size questions [Power / Sample Size]

posted by BE-proff – Russia, 2020-11-04 08:21 (221 d 07:19 ago) – Posting: # 22054
Views: 864

Hi All :waving:

I have a couple of questions:
  1. I wanna do BE study in european population but all PK data from literature have been obtained from asian volunteers.
    Is it applicable/correct to use such data for my study sample size calculation? :confused:

  2. We know that the higher number of subjects the higher chances to pass BE. But on the other hand higher subjects will need higher budget which is not good.
    Are there any statstical methods to find the optimal decision in such situations? :ponder:

Complete thread:

Activity
 Admin contact
21,518 posts in 4,498 threads, 1,523 registered users;
online 16 (0 registered, 16 guests [including 7 identified bots]).
Forum time: Sunday 16:41 CEST (Europe/Vienna)

A refund for defective software might be nice,
except it would bankrupt the entire software industry
in the first year.    Andrew S. Tanenbaum

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5