Multiple dose design Sample size [Power / Sample Size]
Dears, I am asking about the factor we determine the sample size in multiple dose studies? Should I estimate sample size based on intra subject variability of Cmin or Cmax or C tau?
Can I pool the CVs to estimate sample size?
Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5! [Ohlbe]
Edit: Post merged with a new (deleted) post of 2020-10-19. Relax; see also this post #9. [Helmut]
- Multiple dose design Sample size Researcher101 2020-10-14 10:21 [Power / Sample Size]