Bioequivalence and Bioavailability Forum

Ratio calculation of fully replicate study [RSABE / ABEL]

posted by Mithu – India, 2020-07-09 12:46 (34 d 10:25 ago) – Posting: # 21663
Views: 1,149

Hello Sir,

» Then$$\overline{I_{11}}=0.5\times(7.578565+7.957261-7.734541-7.204848)=0.2982185$$and$$\overline{T_{11}/R_{11}}=\exp \overline{I_{11}}=\exp 0.2982185=1.347456$$

Thank you Sir, now i understand.

» Which leaves my second question open:
»
» » » Why on earth do you want to use Excel?

Actually sir when we receive PK data from site (CRO), we check by using Excel. That's why i was using Excel for verification. Generally in average BE and partial replicate, we get it verified but for fully replicate study, i could not match the ratio.

This is the story.

thank you for your kind guidance and help.

regards,

Mithu

---

Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5! [Helmut]

Complete thread:

• Ratio calculation of fully replicate study Mithu 2020-07-09 09:18 [RSABE / ABEL] 
  • Ratio calculation of fully replicate study Helmut 2020-07-09 10:51
    • Ratio calculation of fully replicate study Mithu 2020-07-09 11:23
      • Ratio calculation of fully replicate study Helmut 2020-07-09 12:19
        • Ratio calculation of fully replicate studyMithu 2020-07-09 12:46
          • Purpose? Helmut 2020-07-09 13:10
            • Purpose? Mithu 2020-07-09 13:22
              • Purpose? Helmut 2020-07-09 13:56
                • Purpose? jag009 2020-07-09 18:01
                • Purpose? Mithu 2020-07-10 08:00