Ratio calculation of fully replicate study [RSABE / ABEL]

posted by Mithu – India, 2020-07-09 12:46 (34 d 10:25 ago) – Posting: # 21663
Views: 1,149

Hello Sir,

» Then$$\overline{I_{11}}=0.5\times(7.578565+7.957261-7.734541-7.204848)=0.2982185$$and$$\overline{T_{11}/R_{11}}=\exp \overline{I_{11}}=\exp 0.2982185=1.347456$$

Thank you Sir, now i understand.

» Which leaves my second question open:
»
» » » Why on earth do you want to use Excel?

:-) Actually sir when we receive PK data from site (CRO), we check by using Excel. That's why i was using Excel for verification. Generally in average BE and partial replicate, we get it verified but for fully replicate study, i could not match the ratio.

This is the story.

thank you for your kind guidance and help.

regards,

Mithu


Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5[Helmut]

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