Ratio calculation of fully replicate study [RSABE / ABEL]

posted by Mithu – India, 2020-07-09 14:46 (1576 d 07:42 ago) – Posting: # 21663
Views: 5,086

Hello Sir,

❝ Then$$\overline{I_{11}}=0.5\times(7.578565+7.957261-7.734541-7.204848)=0.2982185$$and$$\overline{T_{11}/R_{11}}=\exp \overline{I_{11}}=\exp 0.2982185=1.347456$$


Thank you Sir, now i understand.

❝ Which leaves my second question open:


❝ ❝ ❝ Why on earth do you want to use Excel?


:-) Actually sir when we receive PK data from site (CRO), we check by using Excel. That's why i was using Excel for verification. Generally in average BE and partial replicate, we get it verified but for fully replicate study, i could not match the ratio.

This is the story.

thank you for your kind guidance and help.

regards,

Mithu


Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5[Helmut]

Complete thread:

UA Flag
Activity
 Admin contact
23,278 posts in 4,889 threads, 1,656 registered users;
70 visitors (0 registered, 70 guests [including 10 identified bots]).
Forum time: 21:29 CET (Europe/Vienna)

Science without epistemology is –
insofar as it is thinkable at all –
primitive and muddled.    Albert Einstein

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5