Bioequivalence and Bioavailability Forum • Kenward-Roger ≥ Satterthwaite

Kenward-Roger ≥ Satterthwaite [RSABE / ABEL]

posted by Helmut – Vienna, Austria, 2019-11-08 21:57 (1795 d 14:46 ago) – Posting: # 20771
Views: 9,700

Hi PharmCat,

❝ I thought that Kenward-Roger provide the same DF as Satterthwaite's for one-dimension effects, so as CI for coefficient is one-dimension hypothesis DF should be the same, as it describes in reference paper, may be SAS make any corrections, I don't know...

Try this one:

library(replicateBE) ds <- substr(grep("rds", unname(unlist(data(package = "replicateBE"))), value = TRUE), start = 1, stop = 5) res <- data.frame(rds = 1:length(ds), df.Satt = NA, df.KR = NA) for (j in seq_along(ds)) { res$df.Satt[j] <- method.B(option = 1, print = FALSE, details = TRUE, data = eval(parse(text = ds[j])))$DF res$df.KR[j] <- method.B(option = 3, print = FALSE, details = TRUE, data = eval(parse(text = ds[j])))$DF } res[, 2:3] <- signif(res[, 2:3], 5) print(res, row.names = FALSE)

The EMA’s Method B evaluated by lmer() of package lmerTest. Kenward-Roger’s degrees of freedom ≥ Satterthwaite’s.

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Complete thread:

Missing periods in replicate designs Helmut 2019-10-16 13:14 [RSABE / ABEL]
- Missing periods in replicate designs ElMaestro 2019-10-16 15:10
  - Missing samples Helmut 2019-10-17 10:22
    - Missing ambulatory samples M.tareq 2020-04-09 15:24
      - Missing ambulatory samples Helmut 2020-04-09 16:15
        
        Missing ambulatory samples M.tareq 2020-04-09 16:54
- Missing periods in replicate designs d_labes 2019-10-17 17:22
  - Missing periods in replicate designs ElMaestro 2019-10-17 20:17
    - Missing periods in replicate designs d_labes 2019-10-18 11:48
  - Missing periods in replicate designs Helmut 2019-10-19 14:30
    - Missing periods in replicate designs: save the data? Astea 2019-10-20 14:46
      - Missing periods in replicate designs: save the data? Helmut 2019-10-20 15:23
        
        Missing periods in replicate designs: kill the data? Astea 2019-10-21 01:59
        
        Meaningful data? Helmut 2019-10-21 11:37
- Missing periods in replicate designs Mahmoud 2019-11-06 11:41
  - Kenward-Roger? Helmut 2019-11-06 12:49
    - Kenward-Roger? PharmCat 2019-11-06 14:43
      - Kenward-Roger ≥ SatterthwaiteHelmut 2019-11-08 20:57
        
        Kenward-Roger ≥ Satterthwaite PharmCat 2019-11-08 22:08
      - Kenward-Roger - links mittyri 2019-11-08 22:59
        
        Kenward-Roger - links PharmCat 2019-11-09 00:51
        degrees of freedom Helmut 2019-11-09 16:22
        
        degrees of freedom PharmCat 2019-11-09 19:11