Bioequivalence and Bioavailability Forum • Geometric mean and CV

Geometric mean and CV [Power / Sample Size]

posted by Rocco_M – Mexico, 2019-09-09 13:31 (587 d 12:41 ago) – Posting: # 20557
Views: 4,056
(edited by Rocco_M on 2019-09-09 13:51)

My apology. Not exactly sure I understand what other poster be saying here 100%. If you be plan a parallel based on FIM: if you have one pooled variance from FIM, is it enough to enter into a sample size calculation? Or does one also need have assumption for pooled variance of other arm, and then take calculated variance of difference based on the FIM variance and assumed other arm pooled variance? This is what I do not understand.
-RoccoM.
Mexico

Edit: Please don’t shout! [Helmut]

Complete thread:

Input for CV when small first-in-man has been run Rocco_M 2019-09-03 18:45 [Power / Sample Size]
- Geometric mean and CV Helmut 2019-09-05 14:05
  - Geometric mean and CV Rocco_M 2019-09-05 23:49
    - Geometric mean and CV Helmut 2019-09-06 00:15
      - Geometric mean and CV Rocco_M 2019-09-06 17:49
        
        Geometric mean and CV Helmut 2019-09-06 18:15
        
        Geometric mean and CV ElMaestro 2019-09-06 19:03
        
        Geometric mean and CV Helmut 2019-09-07 09:57
        
        Geometric mean and CVRocco_M 2019-09-09 13:31
        
        Assumptions… Helmut 2019-09-09 14:09
        
        Assumptions… Rocco_M 2019-09-09 16:35
        
        Assumptions… Helmut 2019-09-09 17:19
        
        Assumptions… Rocco_M 2019-09-13 21:28
        
        t-test & Welch-test Helmut 2019-09-14 00:16
        
        sampleN.TOST and CI.BE Rocco_M 2019-09-17 22:02
        
        assumptions vs. realizations Helmut 2019-09-18 11:04