Bioequivalence and Bioavailability Forum • Geometric mean and CV

Geometric mean and CV [Power / Sample Size]

posted by ElMaestro – Denmark, 2019-09-06 21:03 (2477 d 00:40 ago) – Posting: # 20550
Views: 11,950

Hi Hötzi,

❝ 3. 2 group parallel

❝ Only the pooled (total) s²_p. With a tricky mixed-effects model you could

❝ get s²_pT and s²_pR.

2 group parallel: This tricky model may not be so tricky after all, but may be overkill. I believe you will get the same result as you would obtain from doing a plain sample standard deviation on T and R subsets, respectively.

—
Pass or fail!
ElMaestro

Complete thread:

Input for CV when small first-in-man has been run Rocco_M 2019-09-03 18:45 [Power / Sample Size]
- Geometric mean and CV Helmut 2019-09-05 14:05
  - Geometric mean and CV Rocco_M 2019-09-05 23:49
    - Geometric mean and CV Helmut 2019-09-06 00:15
      - Geometric mean and CV Rocco_M 2019-09-06 17:49
        
        Geometric mean and CV Helmut 2019-09-06 18:15
        
        Geometric mean and CVElMaestro 2019-09-06 19:03
        
        Geometric mean and CV Helmut 2019-09-07 09:57
        
        Geometric mean and CV Rocco_M 2019-09-09 13:31
        
        Assumptions… Helmut 2019-09-09 14:09
        
        Assumptions… Rocco_M 2019-09-09 16:35
        
        Assumptions… Helmut 2019-09-09 17:19
        
        Assumptions… Rocco_M 2019-09-13 21:28
        
        t-test & Welch-test Helmut 2019-09-14 00:16
        
        sampleN.TOST and CI.BE Rocco_M 2019-09-17 22:02
        
        assumptions vs. realizations Helmut 2019-09-18 11:04