Geometric mean and CV [Power / Sample Size]

posted by Rocco_M – Mexico, 2019-09-05 23:49  – Posting: # 20545
Views: 1,416

Thanks. But what I Do not understand is, is it even reasonable to use the geometric CV for the reference? Isn’t the CV you want to input into a sample calculation the CV corresponding to the difference of the Test and Reference? Since you do not have the Test group here, I am a bit confused as to what using the geometric CV of only the reference tells you. In your slides, you have a lone that says “if you have only mean and sd of the reference, a pilot study is unavoidable.”

What am I missing?

Thanks.


Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5[Helmut]

Complete thread:

Activity
 Mix view
Bioequivalence and Bioavailability Forum |  Admin contact
19,992 posts in 4,230 threads, 1,375 registered users;
online 6 (0 registered, 6 guests [including 3 identified bots]).
Forum time (Europe/Vienna): 23:04 CET

I’m not a pessimist,
I’m just a well informed optimist.    José Saramago

The BIOEQUIVALENCE / BIOAVAILABILITY FORUM is hosted by
BEBAC Ing. Helmut Schütz
HTML5