Take them both [Power / Sample Size]

posted by mittyri – Russia, 2018-12-24 21:33 (1030 d 01:43 ago) – Posting: # 19715
Views: 1,789

Hi BE-proff,

» From previous studies I have both AUCs and Cmax with their GMR and CVintra.
» Which parameter is better for sample size calculation - AUC or Cmax?

You need to take into account both.
Remember this one? ;-)
The leading metric depends on CV and GMR.

Kind regards,
Mittyri

Complete thread:

Activity
 Admin contact
21,743 posts in 4,546 threads, 1,543 registered users;
online 7 (0 registered, 7 guests [including 4 identified bots]).
Forum time: Wednesday 00:17 CEST (Europe/Vienna)

Mediocrity finds safety in standardization.    Frederick E. Crane

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5