Larger difference between upper and lower limit of 90% CI [Power / Sample Size]

posted by mirza baig  – Mumbai, India, 2018-11-28 16:14 (733 d 17:23 ago) – Posting: # 19654
Views: 2,035

Hello Everyone,

I am new comer on this forum working in bio equivalence department so I just wanted to know that If we got larger difference between 90% CI limit for any primary factor like AUC0-t, AUC 0-infinity or Cmax e.g. lower limit is 90% and upper limit is 120% so what could be the predictions about the factors that widen the limit (both factor in vitro or in vivo).


Response will be highly appreciated


Edit: category changed [Ohlbe]

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