Group Effect in Full Replicate Design [RSABE / ABEL]

posted by GM – India, 2018-09-12 11:23 (908 d 09:37 ago) – Posting: # 19275
Views: 4,719

» » » What do you mean by “checked”? Have group – together with some nested terms – as part of the model (only report the MSEs, p-values) or do you additionally want to base any decision on it? That’s not a good idea, since power might be compromised and the Type I Error inflated (see this presentation).
» »
» » Sorry for poor english.
»
» No worries. Mine is hardly better. But please answer my question.

We don't want to take any decisions on the basis of model terms.

Our thought is, we need to check group effect for both ABE and RSABE also.

If this correct, how the model is to be designed for RSABE?

Thank you in advance.

Best Regards,
GM

Complete thread:

Activity
 Admin contact
21,371 posts in 4,463 threads, 1,495 registered users;
online 11 (0 registered, 11 guests [including 2 identified bots]).
Forum time: Monday 21:00 UTC (Europe/Vienna)

When puzzled, it never hurts to read the primary documents 
a rather simple and self-evident principle that has, nonetheless,
completely disappeared from large sectors
of the American experience.    Stephen Jay Gould

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5