Bioequivalence and Bioavailability Forum • Group Effect in Full Replicate Design

Group Effect in Full Replicate Design [RSABE / ABEL]

posted by GM – India, 2018-09-12 15:23 (2380 d 08:24 ago) – Posting: # 19275
Views: 7,709

❝ ❝ ❝ What do you mean by “checked”? Have group – together with some nested terms – as part of the model (only report the MSEs, p-values) or do you additionally want to base any decision on it? That’s not a good idea, since power might be compromised and the Type I Error inflated (see this presentation).

❝ ❝

❝ ❝ Sorry for poor english.

❝

❝ No worries. Mine is hardly better. But please answer my question.

We don't want to take any decisions on the basis of model terms.

Our thought is, we need to check group effect for both ABE and RSABE also.

If this correct, how the model is to be designed for RSABE?

Thank you in advance.

—
Best Regards,
GM

Complete thread:

Group Effect in Full Replicate Design GM 2018-09-12 07:17 [RSABE / ABEL]
- Group Effect in Full Replicate Design Helmut 2018-09-12 11:20
  - Group Effect in Full Replicate Design GM 2018-09-12 12:32
    - Group Effect in Full Replicate Design Helmut 2018-09-12 13:08
      - Group Effect in Full Replicate DesignGM 2018-09-12 13:23
        
        Group Effect in Full Replicate Design Helmut 2018-09-12 15:09
        
        Group Effect in Full Replicate Design GM 2018-09-12 15:19
        
        Group Effect in Full Replicate Design Helmut 2018-09-12 15:31
        
        Group Effect in Replicate Design zizou 2018-09-12 23:30
        
        Group Effect in Replicate Design Helmut 2018-09-13 11:34