CV from CI [Power / Sample Size]

posted by Louis52 – 2018-02-04 15:38 (2320 d 18:02 ago) – Posting: # 18341
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Hi Helmut,
Thank you for the explanation :-)
Probably, most of the times we would actually know the PE from a previous study together with the CI. That's why I would not see the need the recalculate the PE (as the GMR for either AUCs or Cmaxs). But I completely agree that if we get from a published article only the information about the GMR limits for AUC or Cmax, then this is a very clever way of deriving the CVintra.
Couple of more questions:
  1. Presumably, n1 and n2 are form the previous study, right?
  2. Where 0.91 and 1.15 are coming from? Did you select them just as an example or there is a particular reason?
Thanks!

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