Scientific gut feeling [Two-Stage / GS Designs]

posted by d_labes  – Berlin, Germany, 2017-11-15 11:34 (1958 d 06:49 ago) – Posting: # 17981
Views: 7,809

Dear Helmut,

My gut feeling tells me:

Woman are better in gut feeling, NLYW especially :-D.

❝ The adjusted α showed (well, in simulations…) that the TIE is controlled if we follow the frameworks exactly, i.e., initiate the second stage only if necessary based on the interim and with the re-estimated sample size. If we increase the sample size, the chance of passing BE increases and hence, the TIE.

Wait, wait ... I will be back in 5 min :cool: with some quick shoot code to verify your claim.

Meanwhile prepare a decision scheme with two metrics. So that I can see if my implementation is correct. My brain gets crowded if I think about the decision scheme. So many "What if". And here you are trained as scuba diver I was told from somebody ;-).



Complete thread:

UA Flag
 Admin contact
22,552 posts in 4,724 threads, 1,606 registered users;
18 visitors (0 registered, 18 guests [including 7 identified bots]).
Forum time: 19:23 CEST (Europe/Vienna)

Learning of many things
does not teach intelligence.    Heraclitus of Ephesus

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz