Bioequivalence and Bioavailability Forum • Canada: Sample size for Cmax: R-code?

Canada: Sample size for Cmax: R-code? [Power / Sample Size]

posted by VStus – Poland, 2017-01-19 11:10 (3089 d 09:44 ago) – Posting: # 16981
Views: 7,424

Dear Helmut,

❝ Don’t agree. It’s easy enough through simulations (i.e., θ₀ 0.95, CV_intra 40%, n 12, power 82.2%).

Can such a simulation be performed using PowerTOST? If no, can you please give some insight on R-code to do the task?

Thank you very much in advance!
Regards, VStus

Complete thread:

Canada: Sample size for Cmax? Helmut 2012-12-18 18:04 [Power / Sample Size]
- Canada: IUT violated? d_labes 2012-12-19 14:00
  - Canada: IUT violated? Helmut 2012-12-29 15:59
    - IUT d_labes 2012-12-31 13:36
- Canada: Sample size for Cmax: R-code?VStus 2017-01-19 10:10
  - Canada: Sample size for Cmax: R-code? zizou 2017-01-19 12:20
  - HC: Sample size for AUC and Cmax: exact and sim’s Helmut 2017-01-19 12:30
    - HC: Sample size for AUC and Cmax: exact and sim’s VStus 2017-01-31 13:44