Bioequivalence and Bioavailability Forum

Hi Junhao,

you can try to get it from the the Publishers (Dustri-Verlag, contact Petra Estner). Alternatively you could ask Dieter Hauschke for a copy.
If that doesn’t work I can scan my copy (will be lousy: yellowed and with notes in the margins…).
It is a very interesting paper if you want to understand the background of sample size estimation. For practical use less so. The tables are for 70/80/90% power, T/R-ratios of 0.85–1.20 (step size 0.05), and CVs of 5–30% (step size 2.5%). Power curves are highly nonlinear. If you want anything which is not covered in the tables, interpolation is not a good idea.
If you want to estimate sample sizes for any desired power, ratio, and CV I recommend the package PowerTOST for R (freeware!). In PowerTOST many designs are covered (two parallel groups, paired means, crossovers: 2×2×2, 3×3, 3×6×3, replicates: 2×2×4, 2×2×3, 2×4×4, partial 2×3×3, Balaam’s 2×4×2, Liu’s 2×2×2). Additionally to power / sample size for conventional average bioequivalence other methods are supported: Reference-scaling for HVD(P)s according to the FDA’s, EMA’s, and ANVISA’s requirements; RSABE for NTIDs (FDA); noninferiority, ratio of means (Fieller’s CI), dose proportionality (power model). Check out the online-manual.