PE outside the acceptance range [Power / Sample Size]
Hi Jay,
I guess this was a 3×3 Latin Square or a 6×3 Williams’ design? Otherwise I don’t come close to your numbers. Post hoc power of a pilot study is even more useless than the one of a pivotal study. However, with a PE of Cmax outside of the acceptance range I would strongly suggest to reformulate.
❝ It is pilot study with sample size of 18, with N=18, the GMR and IS %CV values for Cmax, AUCt and AUCinf are 127.8 & 21.01, 105.1 & 16.71 and 105.49 & 16.73. The post hoc power observed is 2.4, 92.15 and 91.21 respectively.
I guess this was a 3×3 Latin Square or a 6×3 Williams’ design? Otherwise I don’t come close to your numbers. Post hoc power of a pilot study is even more useless than the one of a pivotal study. However, with a PE of Cmax outside of the acceptance range I would strongly suggest to reformulate.
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Helmut Schütz
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Dif-tor heh smusma 🖖🏼 Довге життя Україна!
![[image]](https://static.bebac.at/pics/Blue_and_yellow_ribbon_UA.png)
Helmut Schütz
![[image]](https://static.bebac.at/img/CC by.png)
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- Post hoc Power Jay 2016-01-08 06:49 [Power / Sample Size]
- Post hoc Power ElMaestro 2016-01-08 15:07
- Post hoc Power Helmut 2016-01-09 14:21
- Post hoc Power Jay 2016-01-11 10:59
- PE outside the acceptance rangeHelmut 2016-01-11 14:02
- PE outside the acceptance range Jay 2016-01-13 08:24
- Power for PE outside the acceptance range d_labes 2016-01-13 11:59
- PE at border of the AR: power ≡ 0.05 Helmut 2016-01-13 12:38
- PE at border of the AR: power ≡ 0.05 ? d_labes 2016-01-13 13:21
- PE at border of the AR: power ≤0.05! Helmut 2016-01-14 01:29
- UMP - uniformly more powerful test d_labes 2016-01-15 20:08
- PE at border of the AR: power ≤0.05! zizou 2016-01-24 22:12
- Smoothing artifact Helmut 2016-01-25 14:15
- PE at border of the AR: power ≤0.05! Helmut 2016-01-14 01:29
- PE at border of the AR: power ≡ 0.05 ? d_labes 2016-01-13 13:21
- PE outside the acceptance range Jay 2016-01-13 08:24
- PE outside the acceptance rangeHelmut 2016-01-11 14:02
- Post hoc Power Jay 2016-01-11 10:59