Post hoc Power [Power / Sample Size]
Hi Jay,
First of all, I think you should mention how you calculate post-hoc power. Do you use GMR=0.95, GMR=1.0 or observed?
Anyways, low post-hoc power could be due to deviating GMR (for the case you use the observed GMR; this is likely a product failure) or it could be due to high variability, or both.
If you have a situation with deviating Cmax point estimate but OK AUCt point estimate, then you are facing a challenge.
Having said all, I must admit I am also in the camp of people who think post-hoc power is either rubbish or of very limited value.
❝ As per discussions previous posts, the post of power is not taken into much consideration.
❝ But when the post hoc power of AUCt and AUCinf is observed around 90-100% while the posthoc power of Cmax is less than 20%, then what would be the probable reason for the same.
First of all, I think you should mention how you calculate post-hoc power. Do you use GMR=0.95, GMR=1.0 or observed?
Anyways, low post-hoc power could be due to deviating GMR (for the case you use the observed GMR; this is likely a product failure) or it could be due to high variability, or both.
If you have a situation with deviating Cmax point estimate but OK AUCt point estimate, then you are facing a challenge.
Having said all, I must admit I am also in the camp of people who think post-hoc power is either rubbish or of very limited value.
—
Pass or fail!
ElMaestro
Pass or fail!
ElMaestro
Complete thread:
- Post hoc Power Jay 2016-01-08 06:49 [Power / Sample Size]
- Post hoc PowerElMaestro 2016-01-08 15:07
- Post hoc Power Helmut 2016-01-09 14:21
- Post hoc Power Jay 2016-01-11 10:59
- PE outside the acceptance range Helmut 2016-01-11 14:02
- PE outside the acceptance range Jay 2016-01-13 08:24
- Power for PE outside the acceptance range d_labes 2016-01-13 11:59
- PE at border of the AR: power ≡ 0.05 Helmut 2016-01-13 12:38
- PE at border of the AR: power ≡ 0.05 ? d_labes 2016-01-13 13:21
- PE at border of the AR: power ≤0.05! Helmut 2016-01-14 01:29
- UMP - uniformly more powerful test d_labes 2016-01-15 20:08
- PE at border of the AR: power ≤0.05! zizou 2016-01-24 22:12
- Smoothing artifact Helmut 2016-01-25 14:15
- PE at border of the AR: power ≤0.05! Helmut 2016-01-14 01:29
- PE at border of the AR: power ≡ 0.05 ? d_labes 2016-01-13 13:21
- PE outside the acceptance range Jay 2016-01-13 08:24
- PE outside the acceptance range Helmut 2016-01-11 14:02
- Post hoc Power Jay 2016-01-11 10:59