“classical” GSD alpha's [Two-Stage / GS Designs]
Dear Helmut, dear Ben!
Two-sided or not two-sided, that is the question!
gives us:
gives us:
simsalabim Ben's preferred values.
I personally opt for two-sided
.
BTW: Lan/deMets spending function is Pocock like.
Nearer to original Pocock are the mean of the critical values. Try
simsalabim, Pocock's natural constant! Nearly.
hokus pokus fidibus, Ben's magical number!
Two-sided or not two-sided, that is the question!
library(ldbounds)
# two-sided, check via summary()
bds2.poc <- bounds(t=c(0.5,1), iuse=c(2,2), alpha=rep(0.025,2))
summary(bds2.poc)
2*(1-pnorm(bds2.poc$upper.bounds))
gives us:
[1] 0.03100573 0.02774015
# one-sided
bds1.poc <- bounds(t=c(0.5,1), iuse=2, alpha=0.05)
summary(bds1.poc)
1-pnorm(bds1.poc$upper.bounds)
gives us:
[1] 0.03100573 0.02972542
simsalabim Ben's preferred values.
I personally opt for two-sided

BTW: Lan/deMets spending function is Pocock like.
Nearer to original Pocock are the mean of the critical values. Try
2*(1-pnorm(rep(mean(bds2.poc$upper.bounds),2)))
simsalabim, Pocock's natural constant! Nearly.
(1-pnorm(rep(mean(bds1.poc$upper.bounds),2)))
hokus pokus fidibus, Ben's magical number!
—
Regards,
Detlew
Regards,
Detlew
Complete thread:
- Adaptive TSD vs. “classical” GSD Helmut 2015-11-27 19:05 [Two-Stage / GS Designs]
- Adaptive TSD vs. “classical” GSD ElMaestro 2015-11-27 19:54
- “classical” GSD - E[n] d_labes 2015-11-30 11:15
- Apples are pears by comparing the weight Helmut 2015-12-01 16:35
- Apples are pears by comparing the weight d_labes 2015-12-03 09:16
- Apples are pears by comparing the weight Helmut 2015-12-03 13:10
- Oranges d_labes 2015-12-03 13:56
- Apples are pears by comparing the weight Helmut 2015-12-03 13:10
- Apples are pears by comparing the weight d_labes 2015-12-03 09:16
- Apples are pears by comparing the weight Helmut 2015-12-01 16:35
- Adaptive TSD vs. “classical” GSD Ben 2015-12-02 19:27
- Adaptive TSD vs. “classical” GSD Helmut 2015-12-03 03:11
- “classical” GSD alpha'sd_labes 2015-12-03 09:47
- N sufficiently large‽ Helmut 2015-12-03 14:56
- An other one with 0.0304 d_labes 2015-12-03 16:15
- An other one with 0.0304 Helmut 2015-12-03 16:26
- An other one with 0.0304 d_labes 2015-12-03 16:15
- N sufficiently large‽ Helmut 2015-12-03 14:56
- Adaptive TSD vs. “classical” GSD Ben 2016-01-10 12:43
- “classical” GSD alpha'sd_labes 2015-12-03 09:47
- Adaptive TSD vs. “classical” GSD Helmut 2015-12-03 03:11