Bioequivalence and Bioavailability Forum

Dear Detlew,

❝ […] (because he doesn't go behind the cap)

Exactly.

❝ limits <- scABEL(CV=CV[k],regulator="EMA")

❝ LL <- limits[1]

❝ UL <- limits[2]

That’s elegant!

❝ BTW: What would you do all your times if PowerTOST wasn't build ?

Likely still use the non-central t.
In PowerTOST it takes less than 30 seconds to come up with edu­ca­tio­nal stuff like this (annotation of axes inten­tion­ally suppressed):

That’s why R is “a free software environment for statistical com­puting and graphics”.

I’m even more grateful for Power2Stage! I still remember when I simulated individual ratios for TSDs. In summer 2012 vali­dating Mme Potvin’s ‘Method B’ with a narrow grid (8.25·10⁸ simu­lations) took five weeks (four simul­taneous sessions on each of three machines running 24/7). The summer was hot and I don’t have AC in my office. All the time I was fearing that one of the main­boards would melt. With Power2Stage the same grid takes three hours (one session on one machine). That’s >3,000 times faster… PowerTOST/Power2Stage rulez!