Old beliefs die hard [Two-Stage / GS Designs]
Hi Hötzi,
that was another good post. To state it a little differently:
We are trying to build confidence in the point estimate, this is the whole point of the (any) BE study. At a time when we have very little confidence in it we will not be rewarded from trying to make use of it. That is in a nutshell why the two-stage approaches do not work when we try to use the PE from stage 1.
I think we need it published, or some other way to get the message across. Telling companies that it doesn't work, well... doesn't work.
"Mr. Birdsong is not helping the project forward." vs "Mr. Birdsong is offering an opportunity to avoid a sad and brainless waste of money." The interpretation is commonly the former, rarely the latter
that was another good post. To state it a little differently:
We are trying to build confidence in the point estimate, this is the whole point of the (any) BE study. At a time when we have very little confidence in it we will not be rewarded from trying to make use of it. That is in a nutshell why the two-stage approaches do not work when we try to use the PE from stage 1.
I think we need it published, or some other way to get the message across. Telling companies that it doesn't work, well... doesn't work.
"Mr. Birdsong is not helping the project forward." vs "Mr. Birdsong is offering an opportunity to avoid a sad and brainless waste of money." The interpretation is commonly the former, rarely the latter

—
Pass or fail!
ElMaestro
Pass or fail!
ElMaestro
Complete thread:
- Does unequal alpha distribution make sense? Dr_Dan 2015-05-19 08:29 [Two-Stage / GS Designs]
- Maybe; but watch the TIE! Helmut 2015-05-28 15:04
- Advantages d_labes 2015-06-05 09:35
- Advantages ElMaestro 2015-06-05 10:07
- Advantages – performance measure d_labes 2015-06-05 11:21
- Advantages – performance measure Helmut 2015-06-05 13:29
- Advantages – performance measure d_labes 2015-06-05 21:27
- Advantages – performance measure Helmut 2015-06-05 23:29
- Histogram wonder d_labes 2015-06-06 12:58
- Histogram charlatanry Helmut 2015-06-09 13:43
- Histogram beauty d_labes 2015-06-09 14:55
- Histogram beast Helmut 2015-06-09 15:24
- Histogram beauty d_labes 2015-06-09 14:55
- Histogram charlatanry Helmut 2015-06-09 13:43
- Histogram wonder d_labes 2015-06-06 12:58
- Advantages – performance measure Helmut 2015-06-05 23:29
- Advantages – performance measure d_labes 2015-06-05 21:27
- Advantages – performance measure Helmut 2015-06-05 13:29
- Advantages – performance measure d_labes 2015-06-05 11:21
- Advantages ElMaestro 2015-06-05 10:07
- Advantages d_labes 2015-06-05 09:35
- Does unequal alpha distribution make sense? Dr_Dan 2015-05-29 08:33
- Does unequal alpha distribution make sense? ElMaestro 2015-05-29 09:31
- Does unequal alpha distribution make sense? nobody 2015-05-29 12:56
- Old beliefs die hard Helmut 2015-05-29 13:27
- Old beliefs die hard nobody 2015-05-29 13:41
- Old beliefs die hard Helmut 2015-05-29 18:08
- Old beliefs die hardElMaestro 2015-05-29 18:57
- Old beliefs die hard nobody 2015-05-29 20:06
- ♩ ♪♫♬`·.¸¸.·´`·.¸¸. Helmut 2015-06-02 01:52
- TSD only an option in exceptional cases Dr_Dan 2015-06-02 08:00
- TSD only an option in exceptional cases nobody 2015-06-02 09:23
- TSD only an option in exceptional cases Dr_Dan 2015-06-02 08:00
- Old beliefs die hardElMaestro 2015-05-29 18:57
- Old beliefs die hard Helmut 2015-05-29 18:08
- Old beliefs die hard nobody 2015-05-29 13:41
- Old beliefs die hard Helmut 2015-05-29 13:27
- Does unequal alpha distribution make sense? nobody 2015-05-29 12:56
- Does unequal alpha distribution make sense? ElMaestro 2015-05-29 09:31
- Banana splits Helmut 2015-06-02 00:48
- Maybe; but watch the TIE! Helmut 2015-05-28 15:04