CVinter (or CVtotal) from CVintra [Power / Sample Size]
Hi John John,
No. There is no relationship between those. For examples see the end of this post. Please forget CVinter. In planning a crossover study you need CVintra and for a parallel study CVtotal.
In 2012 I reviewed a manuscript claiming such a relationship (well: The other way ’round – estimating CVintra from CVtotal). All [sic] reviewers rejected the manuscript.
Obviously the authors were more successful in a journal with a lower impact factor… I think that it’s crap, but if you want to have a look:
❝ Knowing the intrasubject variability is there any way to extrapolate the intersubject variability?
No. There is no relationship between those. For examples see the end of this post. Please forget CVinter. In planning a crossover study you need CVintra and for a parallel study CVtotal.
![[image]](img/uploaded/image649.png)
Obviously the authors were more successful in a journal with a lower impact factor… I think that it’s crap, but if you want to have a look:
Ramírez E, Abraira V, Guerra P, Borobia AM, Duque B, López JL, Mosquera B, Lubomirov R, Carcas AJ, Frías J. A Preliminary Model to Avoid the Overestimation of Sample Size in Bioequivalence Studies. Drug Res. 2013;63(2):98–103. doi:10.1055/s-0032-1333296.
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Helmut Schütz
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Dif-tor heh smusma 🖖🏼 Довге життя Україна!
![[image]](https://static.bebac.at/pics/Blue_and_yellow_ribbon_UA.png)
Helmut Schütz
![[image]](https://static.bebac.at/img/CC by.png)
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- Extrapolation john john 2015-05-13 13:36 [Power / Sample Size]
- CVinter (or CVtotal) from CVintraHelmut 2015-05-13 14:33
- CVinter (or CVtotal) from CVintra nobody 2015-05-13 14:53
- OT: Drug Res Helmut 2015-05-13 15:11
- OT: Drug Res nobody 2015-05-13 15:18
- completely OT Helmut 2015-05-13 15:29
- completely OT nobody 2015-05-13 15:37
- completely OT Helmut 2015-05-13 15:29
- OT: Drug Res nobody 2015-05-13 15:18
- OT: Drug Res Helmut 2015-05-13 15:11
- CVinter (or CVtotal) from CVintra john john 2015-05-14 12:16
- CVtotal ≠ CVintra + CVinter Helmut 2015-05-15 13:05
- CVtotal ≠ CVintra + CVinter john john 2015-05-15 13:13
- CVtotal ≠ CVintra + CVinter Helmut 2015-05-15 13:14
- CVtotal ≠ CVintra + CVinter john john 2015-05-15 13:50
- CVtotal ≠ CVintra + CVinter Helmut 2015-05-15 14:07
- CVtotal ≠ CVintra + CVinter john john 2015-05-15 15:07
- CVtotal ≠ CVintra + CVinter Helmut 2015-05-15 15:10
- CVtotal ≠ CVintra + CVinter john john 2015-05-15 15:07
- CVtotal ≠ CVintra + CVinter Helmut 2015-05-15 14:07
- CVtotal ≠ CVintra + CVinter john john 2015-05-15 13:50
- CVtotal ≠ CVintra + CVinter Helmut 2015-05-15 13:14
- CVtotal ≠ CVintra + CVinter john john 2015-05-15 13:13
- CVtotal ≠ CVintra + CVinter Helmut 2015-05-15 13:05
- CVinter (or CVtotal) from CVintra nobody 2015-05-13 14:53
- CVinter (or CVtotal) from CVintraHelmut 2015-05-13 14:33