Sample size for PK linearity [Power / Sample Size]

posted by Lucas – Brazil, 2014-10-13 22:36 (3856 d 06:38 ago) – Posting: # 13694
Views: 14,662

Hello Detlew! I hope I find you well.

❝ Not interested in an answer of others?


Not at all, sorry for that. HS was the one explaining to the OP how to do it, but any response would be great. I had to leave work for a few days and only now have seen your response. Thank you very much for it, very sorry for the late response of mine.

❝ If you have the paper you linked to I would happy to get a copy. Then it may eventually possible to incorporate it into R-package PowerTOST.


Do you still want it? Seems like u've put your hands in it to make the last post, but if not I can e-mail it to you.

We have created a dinamic Excel spreadsheet that calculates the sample size, based on the publication of Sethuraman et al. If you want to see it I could sent it to you also. It is nothing compared to your PowerTOST, since our programming skills here are basic.

❝ Morals of the story: Even the pope may err ;-).


That is where we separate "the children from the adults", or I could say "the button-clickers analysts from the actual analysts/statisticians". Critic sense! :ok:

❝ BTW: New version of R-package PowerTOST3 is out now. From the NEWS: "... Contains further experimental functions for power calculations / samplesize estimation for dose proportionality studies using the Power model".


That's excellent! I'm downloading it now to see.

Again, thank u very much for the help, and excuse my late response!

Best regards.

Lucas

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