Bioequivalence and Bioavailability Forum • “Interim power”

“Interim power” [Two-Stage / GS Designs]

posted by K2K – India, 2013-10-09 14:39 (4645 d 11:49 ago) – Posting: # 11630
Views: 22,914

Dear Sir,

Now I am cleared because of your explanation this doubt is in my head for long time but I hesitate to ask.

Thank you very much.

In PowerTOST actually what formula they used and how to validate PowerTOST from my end.

According to my SOP I want to mention the formula so if possible pls share to me.

Pls guide me.

—
thanks and regards
Karthik

Complete thread:

Potvin’s 2-stage adaptive design GSD 2012-08-17 20:56 [Two-Stage / GS Designs]
- Potvin’s 2-stage adaptive design + RSABE/ABEL Helmut 2012-08-18 00:39
  - Potvin’s 2-stage adaptive design + RSABE/ABEL GSD 2012-08-31 16:30
    - Tough job Helmut 2012-08-31 18:37
      - Tough job GSD 2012-08-31 19:23
        
        C/D for EMA? Good luck! Helmut 2012-09-01 15:09
      - Surprise? d_labes 2012-09-05 12:57
        
        Got it. Ages for sims to complete Helmut 2012-09-05 13:35
        
        Life belt d_labes 2012-09-05 14:51
        
        Life belt Helmut 2012-09-05 15:20
  - Power for Two stage Design K2K 2013-10-07 14:43
    - Power for Two stage Design Helmut 2013-10-07 14:59
      - Power for Two stage Design K2K 2013-10-08 14:35
        
        “Interim power” Helmut 2013-10-08 14:58
        
        “Interim power”K2K 2013-10-09 12:39
        
        Validation of PowerTOST Helmut 2013-10-09 14:10
        Phoenix/WinNonlin - power d_labes 2013-10-09 16:11
        
        Phoenix/WinNonlin - power Helmut 2013-10-09 18:19
        
        power K2K 2013-10-10 08:36