post hoc power [Power / Sample Size]

posted by VSL – India, 2015-07-01 21:37 (3642 d 06:16 ago) – Posting: # 15008
Views: 10,924

Dear,
It has been seen that In protocol, larger sample size is selected to just pass the study without any scientific justification or selecting high T/R in sample size calculation. Therefore, in many cases, post hoc power is more than 100% or nearly 100%. It is like forced bio-equivalence.
Does regulator seek justification for this?
Thanks and Regards...
VSL

Edit: Category changed; see also this post #1. [Helmut]

Complete thread:

UA Flag
Activity
 Admin contact
23,424 posts in 4,927 threads, 1,672 registered users;
32 visitors (0 registered, 32 guests [including 10 identified bots]).
Forum time: 03:54 CEST (Europe/Vienna)

Medical researches can be divided into two sorts:
those who think that meta is better and those
who believe that pooling is fooling.    Stephen Senn

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5