Bioequivalence and Bioavailability Forum

Proc Plan 4x4 crossover [General Sta­tis­tics]

posted by d_labes  – Berlin, Germany, 2012-09-19 18:46 (5017 d 02:31 ago) – Posting: # 9239
Views: 7,614

Dear John,

❝ Do you see anything strange on my 4-way crossover randomization code?

Looking at the result of your code (hope you have checked it by yourself) I noticed that there is not too much random in your randomization .
Just a 6 times repetition of the sequences
1   ADBC
2   DBCA
3   BCAD
4   CADB
May be that some regulators/assessors are not satisfied with that. See Helmut's post on a similar question for a randomization of 2x2 crossover designs.

Try to use random instead of ordered after your factor Subject

Complete thread:

• To learn something new in 2×2 Randomization purvaph 2012-07-04 05:45 
  • Ugly Proc Plan d_labes 2012-07-04 17:06
    • Ugly Proc Plan purvaph 2012-07-24 07:11
    • Ugly Proc Plan jag009 2012-09-18 17:50
      • Proc Plan 4x4 crossoverd_labes 2012-09-19 16:46
        • Proc Plan 4x4 crossover jag009 2012-09-20 21:20
        • Proc Plan 4x4 crossover jag009 2012-09-25 18:07
          • 4x4 crossover - Latin square or Williams d_labes 2012-09-26 11:59