ABE1580
☆    

India,
2012-06-19 11:59
(4300 d 13:14 ago)

Posting: # 8788
Views: 4,581
 

 Replicated design and outlier identification [Outliers]

We are about to conduct a replicate BE study for one of the HVD. Is there any advantage of replicate design over cross-over design to identify outliers?
ABE1580
☆    

India,
2012-06-23 09:49
(4296 d 15:24 ago)

@ ABE1580
Posting: # 8831
Views: 3,709
 

 Replicated design and outlier identification

Dear HS,

Any opinions?

Regards,


Edit: Full quote removed. Please delete anything from the text of the original poster which is not necessary in understanding your answer; see also this post! [Helmut]
Helmut
★★★
avatar
Homepage
Vienna, Austria,
2012-06-23 13:44
(4296 d 11:28 ago)

@ ABE1580
Posting: # 8832
Views: 3,711
 

 Buzzzzz…

❝ Dear HS,


Do you think that I am the only qualified user here and should answer your succinct posts?

❝ Any opinions?


Yes, I do have some. For details see the Policy, second paragraph. Sends me into hibernation.

As an appetizer read:

Schall R, Endrényi L, Ring A. Residuals and Outliers in Replicate Design Crossover Studies. J Biopharmaceut Stat. 2010;20:835–49. doi:10.1080/10543401003618876

Then come back.

Dif-tor heh smusma 🖖🏼 Довге життя Україна! [image]
Helmut Schütz
[image]

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
UA Flag
Activity
 Admin contact
22,957 posts in 4,819 threads, 1,636 registered users;
74 visitors (0 registered, 74 guests [including 8 identified bots]).
Forum time: 00:13 CET (Europe/Vienna)

Nothing shows a lack of mathematical education more
than an overly precise calculation.    Carl Friedrich Gauß

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5